You mean the threaded side that screws into the manifold itself, or the tubing that slips over the barb?
If threaded, you need to use a sealant of some type, teflon tape (5-6 wraps if the crappy white stuff, 2-3 wraps if the decent pink stuff) or some kind of dope like Loctite 567. You want to tighten that down, with wrenches not pliers, not sure of the torque you'd wanna goto, but I'd say if you have more than 3 lines of thread still showing outside the manifold, you might want to tighten it more. fire up the gas, and put the manifold under water, make sure your shutoffs are off. Any leaks are going to be easier to find than with soap or starsan.
If you're talking about gear clamps on the barbs, you might try dipping the gas hose into boiling water, slipping it on the barb and tightening the clamp until it starts to deform the hose a slight bit.