Bag location makes no difference but putting whole hops in a bag may make a slight difference. Pellets will make less of a difference in a bag since you get better utilization. Like others have said overall you probably can't tell that much if any difference!
I have used Fermcap S over the last 10 batches at a rate of 2 drops per gallon with zero boils overs! Works great and no more worries of boil overs especially with 10 gallon batches.